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Chemistry Research<p>When you think of a reaction between an acid and an alcohol, you think of an ester as the product. MacMillan and co-workers from Princeton have now described a different pathway: Selective decarbonylative C-C coupling via a metal-catalyzed photoredox reaction. Read more about this in JACS:</p><p><a href="https://pubs.acs.org/doi/10.1021/jacs.4c15827" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">pubs.acs.org/doi/10.1021/jacs.</span><span class="invisible">4c15827</span></a></p><p><a href="https://mstdn.social/tags/chemistry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>chemistry</span></a> <a href="https://mstdn.social/tags/JACS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>JACS</span></a> <a href="https://mstdn.social/tags/OrgChem" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>OrgChem</span></a> <a href="https://mstdn.social/tags/Science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Science</span></a></p>
Chemistry Research<p>Novel enantioselective <a href="https://mstdn.social/tags/synthesis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>synthesis</span></a> of rubriflordilactone B by Gui and colleagues from the Chinese Academy of Science published in <a href="https://mstdn.social/tags/JACS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>JACS</span></a> <br>This is already the second total synthesis of this group, with an interesting reaction cascade as the key reaction in this process. </p><p><a href="https://mstdn.social/tags/chemistry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>chemistry</span></a> <a href="https://mstdn.social/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>science</span></a> <a href="https://mstdn.social/tags/totalsynthesis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>totalsynthesis</span></a></p><p><a href="https://pubs.acs.org/doi/10.1021/jacs.4c18292" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">pubs.acs.org/doi/10.1021/jacs.</span><span class="invisible">4c18292</span></a></p>
Chemistry Research<p>Joseph Tuccinardi and John Wood from Baylor University (<a href="https://mstdn.social/tags/USA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>USA</span></a>), introduced a novel strategy to efficiently synthesize the core scaffold of aleutianamine. Their study involved a vinylogous Mukaiyama-Michael reaction cascade using two previously unknown coupling partners. Published in <a href="https://mstdn.social/tags/JACS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>JACS</span></a> </p><p><a href="https://me.organicchemistry.eu/post/aleutianamine-jacs-2025/" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">me.organicchemistry.eu/post/al</span><span class="invisible">eutianamine-jacs-2025/</span></a></p><p><a href="https://mstdn.social/tags/orgchem" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>orgchem</span></a> <a href="https://mstdn.social/tags/chemistry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>chemistry</span></a> <a href="https://mstdn.social/tags/totalsynthesis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>totalsynthesis</span></a> <a href="https://mstdn.social/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>science</span></a></p>